PEBL: The Psychology Experiment Building Language
PEBL sounds like an opensource competitor of E-Prime.
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PEBL is software for creating psychology experiments. PEBL offers a simple programming language tailor-made for creating and conducting many standard experiments. It is Free software, licensed under the GPL, with both the compiled executables and source code available without charge. PEBL is available at http://pebl.sf.net.
PEBL is designed to be easily used on multiple computing platforms. Its current implementation uses the SDL as its implementation platform, which is also a cross-platform library that compiles natively under Win32, Linux, and Macintosh Operating Systems.